Abstract: There has been a long history and strong industrial base of design industry in the UK. Especially, London, the capital city of UK, is the world-leading capital of design industry. Based on institutional and cultural perspective, this paper discusses design industry's overall development and regional agglomeration in the UK. Statistical data were collected from the official website of UK design industry and other channels. It shows that support from British government and NGO is very important, and the same is true of good cultural environment for design education. Updating regeneration opportunity of most inner cities in the UK and resource elements converge do good to promoting the prosperity of London design industry. Currently, promotion of design industry should be strengthened from Chinese multi-level government, and more attention is needed to be paid to design and urban regeneration combination.