Abstract: Abstract:With the aid of ArcGIS and GeoDA, the study measured by the index of PCGDP with the methods of Statistic analysis and ESDA. Spatial-temporal pattern and spatial interaction types of county-level economic disparities in Yangtze river Basin during 2001-2011 are preliminarily explored from three aspects:time series, spatial series and impact factors.The results showed:(1)the absolute difference within the Yangtze river basin in volatility to expand, the relative difference is narrowed;the economic development of velocity difference between sub-basins is obvious;Economic differences between the sub-basins presents a decrease trend with fluctuation,regional balanced development began to emerge.(2)the difference of economic development between the sub-basins in the space issignificant,the regional economic development level on the three major economic zones have a significantly differences;The spatial pattern of the economic hotspot area is relative stability in Yangtze river Basin,scope of core area shaped as a circular structures is spreading from east to west in Yangtze river Basin,scope of edge area shaped as a ring structures is decrease.(3)the regional development strategy is the most important factor of economic growth in Yangtze river basin,and give the most influence to the regional difference.