Abstract: Scientific innovation as the first productive force in the development of tourism modernization that is relatively uncontentious. Meanwhile the issue how to effectively promote tourism technology innovation has a great significance effect to the sustainable development of tourism industry. Based on the collaborative theory, this paper constructs the synergetic degree model for the development of the tourism industry and the scientific innovation system, by using this model, the index data of 2006~2014 in JiangSu province were collected to measure the synergetic degree of regional tourism scientific innovation, and the evolution tendency of tourism scientific innovation system was analyzed. The research shows that the synergetic degree of scientific innovation in tourism industry in between [-0.06,0.37] concussion, that means the synergism development level of JiangSu is not high, moreover the research illustrates the scientific and technological innovation of regional tourism synergism mechanism has not yet formed effectively. From the dynamic evolution of the development process, the study reveals the synergetic degree of JiangSu tourism and scientific innovation complex system is raising volatility. Therefore, this paper suggests that relative departments should actively promote the innovation driven strategy, enhance the smart tourism service supply chain, and improve the quality of tourism services and the market conversion of scientific and technological achievements.