Abstract: In the context of economic globalization, the "fast fashion" enterprises gradually become the mainstream supporting power of the clothing retail industry, which partly changed people's consumption concept and consumption behavior, the current pattern of international competition is increasingly fierce, international "fast fashion" enterprises emerge and constantly in the global scope to carry out the space expansion plans. The paper uses the case study method to explore the paths and features of UNIQLO spatial expansion. Study shows that: from the space dimension, UNIQLO follows the "enterprise area spatial expansion phase, cross-regional spatial expansion phase, enterprises transnational spatial expansion phase, the global spatial expansion phase" four stages of the spatial expansion. It shows that different characteristics of the spatial expansion in different expansion stages, mainly including "contagious expansion " and "hierarchy expansion " and " contagious expansion + hierarchy expansion", and diversified expansion, etc. The strategy of spatial expansion will significantly enlighten that of Chinese "fast fashion" enterprises "going out".