Abstract: Abstract: With the aid of ArcGIS and GeoDa, the study measured by the index of PCGDP with the methods of statistic analysis and ESDA. Regional economic disparities in Chengdu-Chongqing Urban Agglomeration since 2000 were analyzed from three aspects:time series, spatial series and impact factors.The results showed:(1)in Chengdu-Chongqing Urban Agglomeration ,the absolute difference continues to expand in fluctuations and the relative difference showing fluctuate narrowing trend ,the high economic value gathering area is relatively stable and have obvious radiation effect ;the whole region presents a balanced development trend ,interval difference made the dominant contribution to the overall differences,though the inner city difference showing a narrowing of trend,it stills at a high level ;(2)the space overall pattern is east-west of country economy in Chengdu-Chongqing Urban Agglomeration,the economic center of gravity gradually tends to the geometric center of gravity,economic development in both the main and secondary direction of a sustained expansion;regional economic level has been significantly improved,the formation of the dual core structure in the high level country,the low level gradually narrowed and mainly distributed in the marginal mountainous counties;the hot spots of economic development in the region are relatively stable and have a certain diffusion effect,while the cold spot is a product word distribution but its scope continues to shrink;(3)the adjustment of industrial structure,regional development strategy,market development and population growth are the main cause of expansion of Chengdu-Chongqing regional economic difference ,but the influence of industrial structure adjustment and population growth on regional differences are relatively profound.