Abstract: Since the founding of the Republic of the Union of Myanmar，the conflict between the central government and the armed forces of ethnic minorities exists continuously. For decades, the armed forces of ethnic minorities have been a difficult problem for the government of Burma, and the ethnic conflicts in Burma are extremely acute, among which the north Myanmar conflict is the most typical. Nowadays, the north Myanmar just conflicts with "The Belt and Road" strategy. Since the Burmese region is the key position for the "The Belt and Road" to South Asia and Southeast Asia, the long-term conflict of Burma region is bound to affect the advancement of the "One Belt and Road" in Myanmar, which further affects the "strategy" in the whole advancement process. Based on the field investigation, questionnaire and interview, the current paper is closely related to the border and its effects in combed with the influence mechanism of "The Belt and Road" the north Myanmar conflict, and draw the following conclusions. On the one hand, the conflict in the northern Burma destroys the bilateral trade channel, affects the Myanmar political stability, increases the investment risk, hinders the development of border trade and thus directly affects the "The Belt and Road" in advance; on the other hand, the conflict in northern Burma will damage the Sino-Burma friendship, invoke the extraterritorial powers involved, and invoke the other countries’ negative coping style, which indirectly influences the advancement of "The Belt and Road". Finally, the related countermeasures for dealing with the influence of the conflict in northern Burma on “the Belt and Road" are given for the purpose of promoting the" The Belt and Road "forward, and achieving the mutual benefit and win-win between China and Burma.