Abstract: After the "Silk Road economic belt" strategy put forward China's economic development has entered a new normal, open area facing new opportunities, especially in the western region as a national strategy for the implementation of key opening to the west, by accelerating interoperability, customs clearance and international logistics Corridor construction, expanding inland and border opening, into the international market and actively participate in global competition, and actively adapt to the new normal. Index system in the western region of opening of this paper to establish a comprehensive system of economic, cultural, social, policy these four aspects, using principal component analysis and weighted average method, respectively, from the time and geographical scale of the opening of the 10 western provinces degree measure and compare the final analysis, the development trend of the opening of each region according to calculation results, the formation of all-round opening pattern make relevant recommendations.