Abstract: With higher education stepping into the popularity development stage, the process of college suburbanization speeds up. It shapes special daily activities space of suburban students. Students in suburban areas relatively lack of internship, leisure and shopping opportunities, which has lead to the inconvenience of students' daily life and unfairness of urban space utilization. Based on this phenomenon, the study gets first-hand data from students’ activity and travel survey in Minhang Campus and Zhongbei Campus, East China Normal University, which was conducted in April, 2016. Methods of case studies, spatial analysis based on GIS and binomial logistic regression model, are used. The study uses standard confidence ellipse to measure students’ activity space in weekdays and weekends. Spatial overlay analysis is used to compare students' activity space and their use of urban space between urban and suburban campuses. The study also analyzes influencing factors of suburban students’ use of urban space to examine their inter-individual differences. The study finds that suburban students travel farther and experience larger activity space than urban students in terms of commuting, leisure and shopping activity. Besides, most students carry out the daily activity, especially commuting activity, within urban areas, no matter which campus they live on. Suburban students’ activities depend on urban areas more at weekends than weekdays due to loose time constraints. Moreover, there are obvious differences in the utilization of urban space by suburban students with different social and economic attributes. The study of students’ activity space will provide empirical basis for planning department about the site of new suburban campuses.