Land use/land cover change is an important issue in the study of global change, and the coastal area is a hot spot region in this field. In this paper, three land use/land cover datasets (MCD12Q1, CCI-LC and GlobeLand30) were used as the research object and a fusion method based on agreement analysis and fuzzy-set theory was adopted to obtain the classification information of land use/land cover along low-middle latitude coastal areas of Eurasia in 2000 and 2010. Then, the variation characteristics and driving factors of land use/land cover were analyzed. Main findings are as follows: land use/land cover change along low-middle latitude coastal areas of Eurasia from 2000 to 2010 was shown that, cropland shrinkage and forest expansion ranked top one, followed by wetland expansion, next were grassland and bare land shrinkage, and lastly shrubland and artificial surfaces expansion. The area of interconversion between land use/land cover types was small, accounting for only 4.22% of the total area of the study area; thereinto, the dominant variation types were the interconversion of cropland, forest and grassland, the interconversion of shrubland and bare land, forest that turned into wetland and forest that turned into shrubland. The regional characteristics of land use/land cover change in various subregions along low-middle latitude coastal areas of Eurasia were different from each other, and the reasons were mainly related to the vegetation types, soil properties, topography, climatic conditions, social conditions and economic levels of each subregion. Although natural driving forces such as terrain, climate, and so on profoundly affected the macro pattern of land use/land cover change, humanistic driving forces such as population growth, economy development, and policy implementation were the direct causes of land use/land cover change along low-middle latitude coastal areas of Eurasia from 2000 to 2010. Overall, this paper fills the gap in the study of land use/land cover change along low-middle latitude coastal areas of Eurasia, and provides information and suggestions for scientific research on man-earth relationship, land resource management, ecological environmental protection and coordinated economic development along low-middle latitude coastal areas of Eurasia.