Water resources conflict is a key scientific issue related to regional security and global sustainable development. With the intensification of global climate change, changes in the spatial and temporal distribution of water resources have led to more complex and uncertain water conflicts. Based on the temporal and spatial distribution characteristics of 1240 water conflicts in the world in the past hundred years, and based on the theories of resource science, economics, international politics, etc., this paper reveals that water conflicts in various regions have their natural ecological, social economic, historical and cultural, and international political roots, and then analyzes the causes of water conflicts from three perspectives: scarcity of resources, internationalization of river basins, asymmetry of water power among countries, and lack and failure of water cooperation mechanisms. Finally, from the perspective of international relations and negotiations, the current solution mechanism is explored, and based on the natural, economic and historical characteristics and development demands of each region, the coordination mechanism and solution suitable for cross-border water resource conflicts are explored through measures such as enhancing regional interest sharing, carrying out comprehensive watershed planning, and strengthening the implementation of international treaties.